Omega-3s and Aging: A Three-Year Trial Shows Promising Results

A large European clinical trial has offered new insights into how omega-3 fatty acids may support healthy aging. The DO-HEALTH study, which followed more than 2,100 adults over the age of 70 across five countries, tested the effects of daily 1 gram of omega-3s, combined with vitamin D and simple strength-training exercises, over a period of three years.

The findings were striking: participants who took the combination of omega-3, vitamin D, and exercise showed slower biological aging, measured through epigenetic markers, compared to those given a placebo. They also experienced fewer infections, fewer falls, and a lower risk of becoming pre-frail—factors that can significantly affect independence and quality of life in older adults.

While more research is needed to understand the long-term benefits, this study underscores the potential of omega-3 supplementation—especially when paired with other healthy lifestyle habits—to play a meaningful role in extending healthspan, not just lifespan.